1. Rupprecht, J.K.,C.-J. Chang, J.M. Cassady, J.L. McLaughlin, K.L.
Mikolajczak, and D.Weisleder, "Asimicin, a new cytotoxic and
pesticidal acetogenin from the paw paw, Asimina triloba (Annonaceae),"
Heterocycles, 24, 1197-1201 (1986).
2. Hui, Y,-H., J.K. Rupprecht, J.E. Anderson, Y.M. Liu, D.L. Smith,
C.-J. Chang, and J.L.McLaughlin. "Bullatalicin, a novel bioactive
acetogenin from Annona bullata (Annonaceae)," Tetrahedron,
45, 6941-6948 (1989).
3. Hui, Y,-H., J.K. Rupprecht, Y-M. Liu, J.E. Anderson, D.L. Smith,
C.-J. Chang, and J.L.McLaughlin, "Bullatacin and bullatacinone:
two highly potent bioactive acetogenins from Annona bullta,"
Journal of Natural Products, 52, 463-477 (1989).
4. Zhao, G.X., Y.-H. Hui, J.K. Rupprecht, J.L. McLaughlin, and K.V.
Wood, "Additional bioactive compounds and trilobacin, a novel
highly cytotoxic acetogenin, from the bark of Asimina triloba,"
Journal of Natural Products, 55, 347-356 (1992).
5. Zhao, G.X., Z.-M. Gu, L. Zeng, J.-F. Chao, K.V. Wood, J.F. Kozlowski,
and J.L. McLaughlin, "The absolute configuration of trilobacin
and trilobin, a novel highly potent acetogenin from the stem bark
of Asimina triloba (Annonaceae)," Tetrahedron 51, 7149-7160
(1995).
6. Rieser, M.J., Y.H. Hui, J.K. Rupprecht, J.F. Kozlowski, K.V.
Wood, J.L. McLaughin, T.R. Hoye, P.R. Hanson, and Z.P. Zhuang, "Determination
of absolute configuration of stereogenic carbinol centers in annonaceous
acetogenins by 1H- and 19F- NMR analysis of Mosher ester derivatives",
Journal of the American Chemical Society, 114,10203-10213 (1992).
7. Lewis, M.A., J.L. Arnason, B.J.R. Philogene, J.K. Rupprecht,
and J.L. McLaughlin. "Inhibition of respiration at site I by
asimicin, an insecticidal acetogenin of the paw paw, Asimina triloba
(Annonaceae)," Pesticide Biochemistry and Physiology, 45, 15-23
(1993).
8. Hollingworth, P.M., K.I. Ahammadsahib, G. Gadelhak, and J.L.
McLaughlin, "New inhibitors of complex I of the mitochondrial
electron transport chain with activity as pesticides", Biochemical
Society Transactions, 22, 230-233 (1994).
9. Ahammadsahib, K.I., R.M. Hollingworth, J.P. McGovren. Y.-H. Hui,
and J.L. McLaughlin. "Mode of action of bullatacin: a potent
antitumor and pesticidal agent", Life Sciences, 53, 1113- 1120(1993).
10. Landoit, J.L., K.I. Ahammadsahib, R.M. Hollingworth, R. Barr,
F.L Crane, N.L. Buerck, G.P. McCabe, and J.L. McLaughlin, "Determination
of structure-activity relationships of annonaceous acetogenins by
inhibition of oxygen uptake in rat liver mitochondria," Chemico-Biological
Interactions, 98, 1-13 (1995).
11. Alfonso, D., H.A. Johnson, T. Colman-Saizarbitoria, C.P. Presley,
G.P. McCabe, and J.L. McLaughlin, "SARs of annonaceous acetogenins
in rat liver mitochondria," Natural Toxins. 4. 181-188 and
erratum 295 (1996).
12. He, K., G.-X.Zhao, G. Shi, L. Zeng, J.-F. Chao, and J.L. McLaughlin,
"Additional bioactive annonaceous acetogenins from Asimina
triloba (Annonaceae)," Bioorganic and Medicinal Chemistry,
5, 501-506 (1997).
13. Morre, D.J., R. de Cabo, C. Fariey, N.H. Oberlies, and J.L.
McLauglin, “Mode of Action of bullatacin, a potent antitumor
acetogenin: inhibition of NADH oxidase activity of HELA and HL-6C
but not liver, plasma membranes," Life Sciences, 56, 343-348
(1995).
14. Satake S., M. Kuzuya, H. Miura, T. Asai, M.A. Ramos, M. Muraguchi,
Y. Ohmoto. and A. Iguchi, "Up-regulation of vascular endothelial
growth factor in response to glucose deprivation." Biology
of the Cell, 90, 161 -168 (1998).
15. Moser, T.L., M.S. Stack, I. Asplin, J.J. Enghild, P. Hojrup,
L. Everitt, S. Hubcnak. H.W, Schnaper, and S.V. Pizzo, "Angiostatin
binds ATP synthase on the surface of human endothelial cells,"
Proceedings of the National Academy of Sciences of the United States
of America. 96. 2811-2816(1999).
16. Morin MJ, "From oncogene to drug: development of small
molecule tyrosine kinase inhibitors and anti-tumor and anti-angiogenic
agents," Oncogene, 19, 6574-6583 (2000).
17. Johnson, H.A., N.H. Oberlies, F.Q. Alali, and J.L. McLaughlin,
"Thwarting resistance:
annonaceous acetogenins as new pesticidal and antitumor agents,"
in Biologically Active Natural Products: Pharmaceuticals ACS Symposium
Book, Las Vegas, Nevada, eds. H. Cutler and S. Cutler, CRC Press,
Boca Raton (1999), pp. 173-183.
18. Oberlies, N.H., F.Q. Alali, and J.L. McLaughlin, "Annonaceous
acetogenins: tnwarting ATP dependent resistance," in New Trends
and Methods in Natural Products Research, eds. I. Calis, T. Ersoz,
and A.A. Basaran, Proceedings of the 12th International Symposium
on Plant Originated Crude Drugs, May 20-22, 1998, The Scientific
and Technical Research Council of Turkey. Ankara pp. 192-223(1999).
19. Oberlies, N.H., C.-J. Chang, and J.L. McLaughlin, "Structure-activity
relationships of diverse annonaceous acetogenins against multidrug
resistant human mammary adenocarcinoma (MCF- 7/adr) cells,"
Journal of Medicinal Chemistry, 40, 2102-2106 (1997).
20. Oberlies, N.H.,V.L. Croy, M.H. Harrison, and J.L.McLaughlin,
'The Annonaceous acetogenin bullatacin is cytotoxic against multidrug
resistant human mammary adenocarcinoma cells," Cancer Letters,
115, 173-179 (1997).
21. Oberlies, N.H., J.L. Jones, T.H. Corbett, S.S. Fotopoulos, J.L.
McLaughlin, "Tumor cell growth inhibition of annonaceous acetogenins
in an in vitro disk diffusion assay, Cancer Letters, 96, 55- 62
(1995).
22. Shimada, H., J.B. Grutzner, J.F. Kozlowski, and J.L. McLaughlin,
"Membrane conformations and their relation to cytotoxicity
of asimicin and its analogues," Biochemistry, 37, 854-866 (1998).
23. Shimada, H., J.F. Kozlowski, and J.L. McLaughlin, "The
positions in liposomal membranes of the tetrahydrofuran ring moieties
of the annonaceous acetogenins, annonacin and sylvaticin, as determined
by ^ NMR spectroscopy," Pharmacological Research, 37, 357-384
(1998).
24. Miyoshi, H., M. Ohshima, H. Shimada, T. Akazi, H. Iwamura, and
J.L. McLaughlin, "Essential structural factors of annonaceous
acetogenins as potent inhibitors of mitochondrial complex I,"
Biochimica Biophysica Acta, 1365, 443-452 (1998).
25. Guadano, A., C. Gutierrez, E. de la Pena, D. Cortes, and A.
Gonzales-Coloma, "Insecticidal and mutagenic evaluation of
two annonaceous acetogenins", Journal of Natural Products,
63, 773-776 (2000).
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